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1943-83-5 - 2-Chloroethyl isocyanate, 97% - A17289 - Alfa Aesar

A17289 2-Chloroethyl isocyanate, 97%

CAS Number
1943-83-5
Synonyms

Size Price ($) Quantity Availability
5g 21.69
25g 67.95
100g 194.40
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2-Chloroethyl isocyanate, 97%

MDL
MFCD00002043
EINECS
217-734-4

Chemical Properties

Formula
ClCH2CH2NCO
Formula Weight
105.52
Boiling Point
135°
Flash Point
56°(132°F)
Density
1.237
Refractive Index
1.4470
Sensitivity
Moisture Sensitive
Solubility
Hydrolyzes in water.

Applications

It is an important raw material and intermediate used in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs.

Notes

Store at 4°C. Incompatible with alcohols. Amines, oxidizing agents. Hygroscopic.

Literature References

John R. Babson. ; Donald J. Reed. Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates.Biochem. Biophys. Res. Commun.. 1978, 83 (2),754-762.

John A. Montgomery.; Ruby. James.; George S. McCaleb.; Thomas P. Johnston. The Modes of Decomposition of 1,3-Bis(2-chloroethyl)-1-nitrosourea and Related Compounds. J. Med. Chem. 1967, 10 (4),668-674.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H330-H334-H314-H318-H226

Fatal if swallowed. Fatal if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapour.

Precautionary Statements: P210-P260-P301+P310-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1071429
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2929.10
TSCA
Yes
RTECS
NQ8450000

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