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10132-07-7 - 4-Amino-2,6-dichloropyrimidine, 98% - A17294 - Alfa Aesar

A17294 4-Amino-2,6-dichloropyrimidine, 98%

CAS Number
10132-07-7
Synonyms

Size Price ($) Quantity Availability
1g 27.00
5g 74.40
25g 297.60
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4-Amino-2,6-dichloropyrimidine, 98%

MDL
MFCD00038015
EINECS
233-369-3

Chemical Properties

Formula
C4H3Cl2N3
Formula Weight
164.00
Melting point
272-274°
Solubility
Slightly soluble in water.

Applications

It is used in the Suzuki coupling of 5-chloro-2-methoxyphenyl boronic acid with 4-amino-2,6-dichloropyrimidine yielded aminochloropyrimidine.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Linus Pauling, et al. Specific hydrogen-bond formation between pyrimidines and purines in deoxyribonucleic acids.Arch. Biochem. Biophys.,1956,65(1), 164-181.

Baoqing Gong, et al. Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-β.Bioorg. Med. Chem. Lett.,2004,14/span>(9), 2303-2308.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2933.59
TSCA
Yes

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