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It finds its application as a protein purification reagent. Triethylamine is used as a competing base for the separation of acidic basic and neutral drugs by reverse-phased high-performance liquid chromatography (HPLC). Triethylamine induces visual disturbances (such as foggy vision) in humans, and is also used in industry as a quenching agent in the ozonolysis of alkenes (e.g. (E)-2-Pentene.
James R. Vaughan, et al. The Preparation of Peptides Using Mixed CarbonicCarboxylic Acid Anhydrides.J. Am. Chem. Soc.,1952,74(3), 676-678.
P. W. Morgan. Synthesis and Properties of Aromatic and Extended Chain Polyamides.Macromolecules.,1977,10/span>(6), 1381-1390.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P280h-P305+P351+P338
Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.