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A17427 4-Bromo-3,5-difluoroanisole, 98%

CAS Number

Stock No. Size Price ($) Quantity Availability
A17427-06 5g 54.50
A17427-14 25g 145.00
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4-Bromo-3,5-difluoroanisole, 98%


Chemical Properties

Formula Weight
Melting point
Refractive Index
Storage & Sensitivity
Ambient temperatures.
Insoluble in water.


It is used to prepare difluorophenacyl analogs as inhibitors of cyclin-dependent kinases. It is also used to synthesize aminopyridine N-oxides for selective inhibition of p38 MAP kinase.


Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

François Crestey, et al. Design and synthesis of a new indazole library: direct conversion of N-methoxy-N-methylamides (Weinreb amides) to 3-keto and 3-formylindazoles.Tetrahedron,2007,63(2), 419-428.

L. W. Lawrence Woo, et al. Synthesis and Structure-Activity Relationship Studies of Derivatives of the Dual Aromatase-Sulfatase Inhibitor 4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate.ChemMedChem.,2013,8(5), 779-799.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code


  • A12139

    Phenylacetylene, 98+%
  • A13986

    Copper(II) sulfate, anhydrous, 98%
  • 12521

    Antimony(III) sulfide, 98% (metals basis)
  • 35834

    Bismuth(III) sulfide, 99.9% (metals basis)
  • 65122

    Sodium sulfide, anhydrous

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