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202865-61-0 - 4-Bromo-3,5-difluoroanisole, 98% - A17427 - Alfa Aesar

A17427 4-Bromo-3,5-difluoroanisole, 98%

CAS Number
202865-61-0
Synonyms

Size Price ($) Quantity Availability
5g 52.90
25g 142.00
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4-Bromo-3,5-difluoroanisole, 98%

MDL
MFCD00143268

Chemical Properties

Formula
C7H5BrF2O
Formula Weight
223.02
Melting point
26-30°
Refractive Index
1.5228
Solubility
Insoluble in water.

Applications

It is used to prepare difluorophenacyl analogs as inhibitors of cyclin-dependent kinases. It is also used to synthesize aminopyridine N-oxides for selective inhibition of p38 MAP kinase.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

François Crestey, et al. Design and synthesis of a new indazole library: direct conversion of N-methoxy-N-methylamides (Weinreb amides) to 3-keto and 3-formylindazoles.Tetrahedron,2007,63(2), 419-428.

L. W. Lawrence Woo, et al. Synthesis and Structure-Activity Relationship Studies of Derivatives of the Dual Aromatase-Sulfatase Inhibitor 4-{[(4-Cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate.ChemMedChem.,2013,8(5), 779-799.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319

Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Harmonized Tariff Code
2909.30
TSCA
No

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