I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
Organic-soluble borohydride. For references to reduction by borohydride, see Sodium borohydride, 35788. Changing the counter ion permits variation in reactivity and selectivity./n
Amides and nitriles are selectively reduced in dichloromethane: Heterocycles, 14, 1437, 1441 (1980); aryl ester, nitro or halo-substituents are unaffected. For the 1,4-reduction of enones, see: Tetrahedron, 37, 1171 (1981). Carboxylic acids can be reduced to alcohols by refluxing in DCM: Synth. Commun., 30, 941 (2000)./n
With reactive halides (e.g. MeI) in DCM, provides a convenient source of diborane: Tetrahedron Lett., 3173 (1972). Hydroboration of alkenes has also been effected by refluxing with the reagent in chloroform: Indian J. Chem., 37B, 1186 (1998)./n
Effective regent for cleavage of TMS ethers: Synth. Commun., 26, 1065 (1996)./n
Hazard Statements: H261-H314-H318
In contact with water releases flammable gas. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P280-P303+P361+P353-P305+P351+P338-P310a-P370+P378i-P402+P404
Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor In case of fire: Use for extinction: Fire-extinguishing powder. Store in a dry place. Store in a closed container.