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Benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) is used in the synthesis of stereoisomers which were evaluated as α- and β- adrenergic antagonists
Magali Massacret.; Catherine Goux.; Paul Lhoste.; Denis Sinou. One-pot preparation of chiral 2-vinyl-1,4-benzodioxane. Tetrahedron Letters. 1994, 35, (33), 6093-6096.
Wendel L. Nelson.; Mark L. Powell.; Donald C. Dyer. Absolute configuration of glycerol derivatives. 7. Enantiomers of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]ethyl]-1,4-benzodioxane (WB-4101), a potent competitive .alpha.-adrenergic antagonist. J. Med. Chem. 1979, 22, (9), 1125-1127.
Hazard Statements: H227
Precautionary Statements: P210-P280-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant