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A17575 Butyryl chloride, 98%

CAS Number
141-75-3
Synonyms
Butanoyl chloride

Stock No. Size Price ($) Quantity Availability
A17575-18 50g 19.10
A17575-30 250g 31.40
A17575-0B 1000g 95.80
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Butyryl chloride, 98%

MDL
MFCD00000752
EINECS
205-498-5

Chemical Properties

Formula
CH3CH2CH2COCl
Formula Weight
106.55
Melting point
-89°
Boiling Point
101-102°
Flash Point
18°(64°F)
Density
1.026
Refractive Index
1.4120
Storage & Sensitivity
Moisture Sensitive. Ambient temperatures.
Solubility
Miscible with ether.

Applications

Butyryl chloride is used as an intermediate for the synthesis of active pharmaceutical ingredients benzoyl peroxide, t-butyl perbenzoate, and benzophenone. It is also used as an acylation reagent. Further, it is used in the preparation of peroxides such as benzoyl peroxide, benzophenone and t-butyl perbenzoate. In addition to this, it is involved in the preparation of chromones and antiproliferative agents.

Notes

Moisture sensitive. Incompatible with water, alcohols, strong bases and strong oxidizing agents

Literature References

Britton, J.; Chalker, J. M.; Raston, C. L. Rapid Vortex Fluidics: Continuous Flow Synthesis of Amides and Local Anesthetic Lidocaine. Chem. Eur. J. 2015, 21 (30), 10660-10665.

Robinson, C. W.; Rye, C. S.; Chessum, N. E. A.; Jones, K. A model beta-sheet interaction and thermodynamic analysis of beta-strand mimetics. Org. Biomol. Chem. 2015, 13 (27), 7402-7407.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H302-H314-H331

Highly flammable liquid and vapour. Harmful if swallowed. Causes severe skin burns and eye damage. Toxic if inhaled.

Precautionary Statements: P210-P233-P240-P241-P242-P243-P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1598
Beilstein
605395
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
Yes
RTECS
EM0595000

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