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141-75-3 - Butyryl chloride, 98% - Butanoyl chloride - A17575 - Alfa Aesar

A17575 Butyryl chloride, 98%

CAS Number
141-75-3
Synonyms
Butanoyl chloride

Size Price ($) Quantity Availability
50g 18.10
250g 29.90
1000g 91.20
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Butyryl chloride, 98%

MDL
MFCD00000752
EINECS
205-498-5

Chemical Properties

Formula
CH3CH2CH2COCl
Formula Weight
106.55
Melting point
-89°
Boiling Point
101-102°
Flash Point
18°(64°F)
Density
1.026
Refractive Index
1.4120
Sensitivity
Moisture Sensitive
Solubility
Miscible with ether.

Applications

Butyryl chloride is used as an intermediate for the synthesis of active pharmaceutical ingredients benzoyl peroxide, t-butyl perbenzoate, and benzophenone. It is also used as an acylation reagent. Further, it is used in the preparation of peroxides such as benzoyl peroxide, benzophenone and t-butyl perbenzoate. In addition to this, it is involved in the preparation of chromones and antiproliferative agents.

Notes

Moisture sensitive. Incompatible with water, alcohols, strong bases and strong oxidizing agents

Literature References

Britton, J.; Chalker, J. M.; Raston, C. L. Rapid Vortex Fluidics: Continuous Flow Synthesis of Amides and Local Anesthetic Lidocaine. Chem. Eur. J. 2015, 21 (30), 10660-10665.

Robinson, C. W.; Rye, C. S.; Chessum, N. E. A.; Jones, K. A model beta-sheet interaction and thermodynamic analysis of beta-strand mimetics. Org. Biomol. Chem. 2015, 13 (27), 7402-7407.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H331-H302-H314-H318

Highly flammable liquid and vapour. Toxic if inhaled. Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P210-P260-P261-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dust/fume/gas/mist/vapours/spray. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1598
Beilstein
605395
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2915.90
TSCA
Yes
RTECS
EM0595000

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