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371-42-6 - 4-Fluorothiophenol, 98+% (dry wt.), water <7% - 4-Fluorobenzenethiol - A17600 - Alfa Aesar

A17600 4-Fluorothiophenol, 98+% (dry wt.), water <7%

CAS Number
371-42-6
Synonyms
4-Fluorobenzenethiol

Size Price ($) Quantity Availability
5g 42.12
25g 105.20
100g 282.67
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4-Fluorothiophenol, 98+% (dry wt.), water <7%

MDL
MFCD00004846
EINECS
206-737-6

Chemical Properties

Formula
C6H5FS
Formula Weight
128.17
Boiling Point
170-172°
Flash Point
57°(135°F)
Density
1.203
Refractive Index
1.5500
Sensitivity
Air Sensitive
Solubility
Not miscible or difficult to mix in water.

Applications

It is used in the synthesis of Bicalutamide, an anti-cancer drug.

Notes

Air Sensitive. Keep away from oxidizing agents and air. Store under inert gas.

Literature References

Bang-Chi Chen.; Rulin Zhao.; Stacey Gove.; Bei Wang.; Joseph E. Sundeen.; Mark E. Salvati.; and Joel C. Barrish. Nucleophilic Aromatic Substitution of Methacrylamide Anion and Its Application to the Synthesis of the Anticancer Drug Bicalutamide.J. Org. Chem.,2003,68(26), 10181-10182.

Wenting Dong.; Wendell Rhine.; Greg Caggiano.; Owen R. Evans.; George Gould.; John White.; Jeff Sharp.; Pat Gilbert.; Shreyashi Ganguly and Stephanie L. Brock. Characterization of bismuth telluride aerogels for thermoelectric applications.Cambridge Journals Online; MRS Proceedings, 2011,1036.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H310-H331-H315-H319-H317-H335-H226-H400-H410

Fatal if swallowed. Fatal in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation. Flammable liquid and vapour. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Precautionary Statements: P262-P273-P280h-P305+P351+P338-P309+P311-P501a

Do not get in eyes, on skin, or on clothing. Avoid release to the environment. Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1446350
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2930.90
TSCA
No

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