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Sodium thiosulfate is used in volumetric analysis to estimate the concentration of certain compounds in solution (hydrogen peroxide) as well as chlorine content in bleaching powder and water. It is used to prepare S-alkylthiosulfonates. Furthermore, it is used in the tanning of leather and in photographic processing. It is used as an antidote to cyanide poisoning and acts as a safe disposal medium in chemistry laboratories when working with bromine, iodine and other strong oxidizers. It is an important component in hand warmers and heating pads.
Wendroth, S. M.; Heady, T. N.; Haverstick, D. M.; Bachmann, L. M.; Scott, M. G.; Boyd, J. C.; Bruns, D. E. Falsely increased chloride and missed anion gap elevation during treatment with sodium thiosulfate. Clin. Chim. Acta 2014, 431, 77-79.
Chen, N. X.; ONeill, K.; Akl, N. K.; Moe, S. M. Adipocyte induced arterial calcification is prevented with sodium thiosulfate. Biochem. Biophys. Res. Commun. 2014, 449 (1), 151-156.