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It is applied in organic synthesis. 5-Nitro-o-toluidine finds application as an intermediate in the synthesis of Pigment Red 17 (C.I. 12 390) and Pigment Red 22 (C.I. 12 315). It is also employed in conjunction with certain C.I. coupling components. It also serves as a precursor for a wide assortment of azo dyes of various red, yellow, orange, violet, and brown hues. It can also be employed as analytical standard for the surfactant mediated transformations (-254nm) of 2,4-dinitrotoluene.
National Toxicology Program. Bioassay of 5-nitro-o-toluidine for possible carcinogenicity (CAS No. 99-55-8).Natl Cancer Inst Carcinog Tech Rep Ser.
Claude A Diehl.; Chad T Jafvert.; Karen A Marley.; Richard A Larson. Surfactant-assisted UV-photolysis of nitroarenes.Chemosphere.2002,46(4), 553-560.
Eva Engel.; Francesco Santarelli.; Rudolf Vasold.; Heidi Ulrich.; Tim Maisch.; Burkhard König.; Michael Landthaler.; Neera V Gopee.; Paul C Howard.; Wolfgang Bäumler. Establishment of an extraction method for the recovery of tattoo pigments from human skin using HPLC diode array detector technology.Anal Chem.2006,78(18),6440-6447.
Hazard Statements: H301-H311-H331-H351
Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. Suspected of causing cancer.
Precautionary Statements: P260-P201-P280h-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.