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A17814 2-Amino-2-methyl-1-propanol, 95%, may cont. ca 5% water

CAS Number

Stock No. Size Price ($) Quantity Availability
A17814-AE 100ml 19.30
A17814-AP 500ml 30.20
A17814-0F 2500ml 97.30
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2-Amino-2-methyl-1-propanol, 95%, may cont. ca 5% water


Chemical Properties

Formula Weight
Melting point
Boiling Point
Flash Point
Refractive Index
Storage & Sensitivity
Ambient temperatures.
Immiscible with water. Miscible with alcohols.


2-Amino-2-methyl-1-propanol is used for the preparation of buffer solution and in cosmetics. It is also used in ATR-FTIR spectroscopic investigation of the carbon monoxide absorption characteristics of a series of heterocyclic diamines.


Incompatible withoxidizing agents, strong acids, copper, brass and aluminum.

Literature References

Buffer and phosphate acceptor in assay of phosphatases: Methods of Enzymatic Analysis, 3rd ed., H. U. Bergmeyer, Ed., Verlag Chemie, Weinheim (1984), vol. 4, p76.

Precursor of 2-substituted-4,4-dimethyl-2-oxazoline derivatives of carboxylic acids: J. Org. Chem., 39, 2787 (1974), developed by Meyers. The oxazoline, which is readily formed with the acid chloride and thionyl chloride, is stable to base, organometallic reagents, etc., but readily cleaved by dilute acid. For further information on the reactivity of these derivatives, see 2,4,4-Trimethyl-2-oxazoline, L00181.

2-Aryl-4,4-dimethyl-2-oxazolines are activated towards ortho-lithiation: J. Org. Chem., 40, 3058 (1975). Methoxy- or fluoro-substituents in the ortho-position are readily substitutied by organolithiums or Grignards, providing a versatile route to biaryls: J. Am. Chem. Soc ., 97, 7383 (1975). For examples, see: Org. Synth. Coll., 9, 258 (1998). The oxazoline can also be converted to an aldehyde by methylation and borohydride reduction.

For reviews of the use of oxazolines in synthesis, see: Angew. Chem. Int. Ed., 15, 270 (1976); Tetrahedron, 41, 837 (1985); 50, 2297 (1994).


Conway, W.; Bruggink, S.; Beyad, Y.; Luo, W.; Cabrera, I. M., Puxty, G.; Feron, P. CO2 absorption into aqueous amine blended solutions containing monoethanolamine (MEA), N, N-dimethylethanolamine (DMEA), N, N-diethylethanolamine (DEEA) and 2-amino-2-methyl-1-propanol (AMP) for post-combustion capture processes. Chem. Eng. Sci. 2015, 126, 446-454.

Halim, H. N. A.; Shariff, A. M.; Bustam, M. A. High pressure CO2 absorption from natural gas using piperazine promoted 2-amino-2-methyl-1-propanol in a packed absorption column. Sep. Purif. Technol. 2015, 152, 87-93.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H315-H319-H336-H373

Combustible liquid. Causes skin irritation. Causes serious eye irritation. May cause drowsiness or dizziness. May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements: P210-P234-P235-P260-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P314-P332+P313-P337+P313-P362-P370+P378q-P390-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep only in original container. Keep cool. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Absorb spillage to prevent material damage. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code


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  • 11599

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  • 14707

    Sodium hydrogen carbonate, ACS, 99.7-100.3%
  • 44529

    Ethylene glycol, Spectrophotometric grade, 99+%

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