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DL-Malic acid is used as a food additive. It is a component of some artificial vinegar flavors. Further, it is used in the preparation of chiral compounds, including κ-opioid rece. It is utilized for chiral resolution by ligand-exchange capillary electrophoresis.
Zhang, Q.; Yang, Y.; Cheng, L.; Cao, C.; Ding, Z.; Wang, C.; Yang, W.; Hu, Y.; Li, Y. Thermodynamic models for determination of the solubility of dl-malic acid in methanol plus (acetonitrile, N,N-dimethylformamide, isopropyl alcohol) binary solvent mixtures. J. Chem. Thermodyn. 2015, 85, 148-154.
Espinosa, K. C.; Cabrera, R. I. G.; López, A. B.; Roldán, M. A. T.; Cruz, N. A. V. Positive effect of reduced aeration rate on growth and stereospecificity of dl-malic acid consumption by Azospirillum brasilense: Improving the shelf life of a liquid inoculant formulation. J. Biotechnol. 2015, 195, 74-81.
Hazard Statements: H302-H315-H318-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.