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111-30-8 - Glutaraldehyde, 25% aq. soln. - Glutaric dialdehyde - Pentanedial - A17876 - Alfa Aesar

A17876 Glutaraldehyde, 25% aq. soln.

CAS Number
111-30-8
Synonyms
Glutaric dialdehyde
Pentanedial

Size Price ($) Quantity Availability
100ml 18.95
500ml 38.48
2500ml 93.32
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Glutaraldehyde, 25% aq. soln.

MDL
MFCD00007025
EINECS
203-856-5

Chemical Properties

Formula
C5H8O2
Formula Weight
100.12
Density
1.062
Refractive Index
1.3730
Solubility
Miscible with water, ethanol, benzene, ether, acetone, dichloromethane, ethylacetate, isopropanol, n-hexane and toluene.

Applications

Glutaraldehyde is used for cross-linking proteins and polyhydroxy materials. Also used as a fixative for tissues and as an amine-reactive homobifunctional crosslinker. It is also used in coupling reaction of biotin hydrazides to nucleic acids which is useful for conjugating fluorescent hydrazides and hydroxylamines to DNA and for stabilization ofproteins on agarose beads,activation of polystyrene and glass, for immobilization of antibodies and antigens.

Notes

Heat and air sensitive. Incompatible with strong acids, strong bases and strong oxidizing agents.

Literature References

For use in the Robinson synthesis of pseudopelletierine, see Acetone-1,3-dicarboxyl­ic acid, A13742.

Reaction with (R)-(-)-2-Phenyl­glycinol, A19030, gives an intermediate for asymmetric synthesis of alkaloids: Org. Synth. Coll., 9, 176 (1998).

Cho, K. L.; Hill, A. J.; Caruso, F.; Kentish, S. E. Chlorine Resistant Glutaraldehyde Crosslinked Polyelectrolyte Multilayer Membranes for Desalination. Adv. Mater. 2015, 27 (17), 2791-2796.

Vikram, A.; Bomberger, J. M.; Bibby, K. J. Efflux as a Glutaraldehyde Resistance Mechanism in Pseudomonas fluorescens and Pseudomonas aeruginosa Biofilms. Antimicrob. Agents Chemother. 2015, 59 (6), 3433-3440.

GHS Hazard and Precautionary Statements

Hazard Statements: H331-H302-H317-H334-H314-H400

Toxic if inhaled. Harmful if swallowed. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes severe skin burns and eye damage. Very toxic to aquatic life.

Precautionary Statements: P260-P285-P261-P273-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,4472
Beilstein
605390
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2912.19
TSCA
Yes
RTECS
MA2450000

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