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Dithizone acts as an indicator for metals. It is also used as a chelating agent for heavy metals like mercury and lead. It is also used to evaluate the purification of human pancreatic islet preparations, which is used for transplantation in patients with type 1 diabetes.
Reagent for extraction of metals. Indicator for metals: Anal. Chim. Acta, 57, 393 (1971).
Saxena, R.; Tiwari, S.; Sharma, N. Flow-injection solid phase extraction using Dowex Optipore L493 loaded with dithizone for preconcentration of chromium species from industrial waters and determination by FAAS. RSC Adv. 2015, 5 (85), 69196-69204.
Zhang, L.; Xiong, Z.; Zhang, L.; Yu, B.; Zhang, W. Magnetic nanoparticles coated with dithizone-modified chitosan for use in solid-phase extraction of copper(II). Anal. Methods 2015, 7 (5), 2050-2054.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P280g-P305+P351+P338-P332+P313
Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation occurs: Get medical advice/attention.