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23676-08-6 - Methyl 4-ethoxybenzoate, 98% - 4-Ethoxybenzoic acid methyl ester - A17980 - Alfa Aesar

A17980 Methyl 4-ethoxybenzoate, 98%

CAS Number
23676-08-6
Synonyms
4-Ethoxybenzoic acid methyl ester

Size Price ($) Quantity Availability
5g 14.02
25g 48.05
100g 185.46
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Methyl 4-ethoxybenzoate, 98%

MDL
MFCD00017264
EINECS
245-817-5

Chemical Properties

Formula
C10H12O3
Formula Weight
180.21
Melting point
35-37°
Boiling Point
160°/20mm
Flash Point
>110°(230°F)
Solubility
Soluble in alcohol and ether. Insoluble in water.

Applications

Methyl 4-ethoxybenzoate is used in the preparation of 4- ethoxybenzoic acid by reacting with aluminum tribromide. It is involved in the preparation of apricoxib, which is a selective cyclooxygenase inhibitor.

Notes

Incompatible with strong oxidizing agents.

Literature References

Lee, J. J.; Pollock III, G. R.; Mitchell, D.; Kasuga, L.; Kraus, G. A. Upgrading malic acid to bio-based benzoates via a Diels-Alder-initiated sequence with the methyl coumalate platform. RSC Adv. 2014, 4 (86), 45657-45664.

Yamanaka, M.; Kobayashi, K. Capsular Assemblies of Calix[4]resorcinarene-based Cavitands. Asian J. Org. Chem. 2013, 2 (4), 276-289.

Other References

Beilstein
2691838
Harmonized Tariff Code
2918.99
TSCA
No

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