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70-18-8 - L-Glutathione, reduced, 97% - gamma-L-Glutamyl-L-cysteinylglycine - GSH - A18014 - Alfa Aesar

A18014 L-Glutathione, reduced, 97%

CAS Number
70-18-8
Synonyms
gamma-L-Glutamyl-L-cysteinylglycine
GSH

Size Price ($) Quantity Availability
5g 38.90
25g 115.00
100g 402.00
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L-Glutathione, reduced, 97%

MDL
MFCD00065939
EINECS
200-725-4

Chemical Properties

Formula
C10H17N3O6S
Formula Weight
307.33
Melting point
ca 193° dec.
Solubility
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Applications

L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.

Notes

Store in cool place. Incompatible with strong oxidizing agents.

Literature References

Calborean, A.; Martin, F.; Marconi, D.; Turcu, R.; Kacso, I. E.; Iarinca, L. B.; Graur, F.; Turcu, I. Adsorption mechanisms of l-Glutathione on Au and controlled nano-patterning through Dip Pen Nanolithography. Mater. Sci. Eng., C 2015, 57, 171-180.

Wang, X.; Chen, X.; Evans, D. G.; Yang, W. A novel biosensor for reduced l-glutathione based on cobalt phthalocyaninetetrasulfonate-intercalated layered double hydroxide modified glassy carbon electrodes. Sens. Actuators, B 2011, 160 (1), 1444-1449.

Other References

Merck
14,4475
Beilstein
1729812
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
MC0556000

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