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A18083 4-Methyl-1H-pyrazole, 97+%

CAS Number
7554-65-6
Synonyms
Fomepizole

Stock No. Size Price ($) Quantity Availability
A18083-03 1g 69.80
A18083-06 5g 266.00
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4-Methyl-1H-pyrazole, 97+%

MDL
MFCD00005245
EINECS
231-445-0

Chemical Properties

Formula
C4H6N2
Formula Weight
82.11
Melting point
13°
Boiling Point
204-207°
Flash Point
96°(204°F)
Density
1.018
Refractive Index
1.4945
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Solubility
Miscible with water, ether, benzene and alcohol.

Applications

4-Methyl-1H-pyrazole is used as an antidote in methanol and ethylene glycol poisoning. It is also employed as an alcohol dehydrogenase inhibitor. It acts a ligand in coordination chemistry. Further, it serves as an intermediate in organic synthesis.

Notes

Hygroscopic. Incompatible withstrong oxidizing agents, strong acids, acid chlorides, acid anhydrides and chloroformates.

Literature References

Vlaicu, I. D.; Olar, R.; Marinescu, D.; Lazar, V.; Badea, M. Physico-chemical and thermal characterisation of new Co(II) complexes with pyrazole derivatives. J. Therm. Anal. Calorim. 2013, 113 (3), 1337-1343.

Boji?, M.; Sedgeman, C. A.; Nagy, L. D.; Guengerich, F. P. Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450. Eur. J. Pharm. Sci. 2015, 73, 49-56.

Finnerty, N.; O'Riordan, S. L.; Klamer, D.; Lowry, J.; Pålsson, E. Increased brain nitric oxide levels following ethanol administration. Nitric Oxide 2015, 47, 52-57.

GHS Hazard and Precautionary Statements

Hazard Statements: H302+H312-H314-H335

Harmful if swallowed. Harmful in contact with skin. Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,4216
Beilstein
105204
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2933.19
TSCA
No
RTECS
UQ7350000

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