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7554-65-6 - 4-Methyl-1H-pyrazole, 97+% - Fomepizole - A18083 - Alfa Aesar

A18083 4-Methyl-1H-pyrazole, 97+%

CAS Number
7554-65-6
Synonyms
Fomepizole

Size Price ($) Quantity Availability
1g 68.60
5g 226.40
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4-Methyl-1H-pyrazole, 97+%

MDL
MFCD00005245
EINECS
231-445-0

Chemical Properties

Formula
C4H6N2
Formula Weight
82.11
Melting point
13°
Boiling Point
204-207°
Flash Point
96°(204°F)
Density
1.018
Refractive Index
1.4945
Sensitivity
Hygroscopic
Solubility
Miscible with water, ether, benzene and alcohol.

Applications

4-Methyl-1H-pyrazole is used as an antidote in methanol and ethylene glycol poisoning. It is also employed as an alcohol dehydrogenase inhibitor. It acts a ligand in coordination chemistry. Further, it serves as an intermediate in organic synthesis.

Notes

Hygroscopic. Incompatible withstrong oxidizing agents, strong acids, acid chlorides, acid anhydrides and chloroformates.

Literature References

Vlaicu, I. D.; Olar, R.; Marinescu, D.; Lazar, V.; Badea, M. Physico-chemical and thermal characterisation of new Co(II) complexes with pyrazole derivatives. J. Therm. Anal. Calorim. 2013, 113 (3), 1337-1343.

Boji?, M.; Sedgeman, C. A.; Nagy, L. D.; Guengerich, F. P. Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450. Eur. J. Pharm. Sci. 2015, 73, 49-56.

Finnerty, N.; O'Riordan, S. L.; Klamer, D.; Lowry, J.; Pålsson, E. Increased brain nitric oxide levels following ethanol administration. Nitric Oxide 2015, 47, 52-57.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,4216
Beilstein
105204
Harmonized Tariff Code
2933.19
TSCA
No
RTECS
UQ7350000

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