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A18115 4-Phenylbutyric acid, 99%

CAS Number
1821-12-1
Synonyms

Stock No. Size Price ($) Quantity Availability
A18115-14 25g 51.40
A18115-22 100g 167.00
A18115-36 500g 689.00
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4-Phenylbutyric acid, 99%

MDL
MFCD00004403
EINECS
217-341-8

Chemical Properties

Formula
C6H5(CH2)3CO2H
Formula Weight
164.20
Melting point
49-53°
Boiling Point
165°/10mm
Flash Point
>110°(230°F)
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water and methanol.

Applications

4-Phenylbutyric acid is used as a chemical chaperone involved in protein-folding disorders. It is involved in the synthesis of dyes and an active pharmaceutical ingredient intermediate.

Notes

Styrene-DVB; Strongly basic gel type resin.Incompatible with strong oxidizing agents.

Literature References

Kolb, P. S.; Ayaub, E. A.; Zhou, W.; Yum, V.; Dickhout, J. G.; Ask, K. The therapeutic effects of 4-phenylbutyric acid in maintaining proteostasis. Int. J. Biochem. Cell Biol. 2015, 61, 45-52.

Hachuła, B.; Jabłońska-Czapla, M.; Flakus, H. T.; Nowak, M.; Kusz, J. H/D isotopic recognition and temperature effects in IR spectra of hydrogen-bonded cyclic dimers in crystals: 3-Methylcinnamic acid and 4-phenylbutyric acid. Spectrochim. Acta, Part A 2015, 134, 592-597.

Other References

Beilstein
638180
Harmonized Tariff Code
2916.39
TSCA
Yes

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