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206658-89-1 - 3-Aminobenzeneboronic acid monohydrate, 97% - 3-Aminophenylboronic acid monohydrate - A18189 - Alfa Aesar

A18189 3-Aminobenzeneboronic acid monohydrate, 97%

CAS Number
206658-89-1
Synonyms
3-Aminophenylboronic acid monohydrate

Size Price ($) Quantity Availability
1g 54.60
5g 194.00
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3-Aminobenzeneboronic acid monohydrate, 97%

MDL
MFCD00149554
EINECS
250-189-0

Chemical Properties

Formula
C6H8BNO2•H2O
Formula Weight
154.96 (136.95anhy)
Melting point
93-97°
Sensitivity
Air & Moisture Sensitive
Solubility
Soluble in DMSO and methanol.

Applications

It is employed as a reagent in the preparation of Suzuki-Miyaura cross-coupling, used for Gram-positive ant virulence drugs and inhibitors of Streptococcus agalactiae Stk1, regioisomer of Zaleplon (a sedative), amphiphilic random glycopolymer, which self-assemble to form nanoparticles, with potential as a glucose-sensitive matrix, chemomechanical polymer that expands and contracts in blood plasma with high glucose selectivity. Aminophenylboronic Acid is also used as a reagent in the preparation of nonbenzodiazepine hypnotic agents.

Notes

Air & Moisture Sensitive. Store away from oxidizing agents, air, water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Gregory D. Cuny.; Maxime Robin.; Natalia P. Ulyanova.; Debasis Patnaik.; Valerie Pique.; Gilles Casano.; Ji-Feng Liu.; Xiangjie Lin.; Jun Xian.; Marcie A. Glicksman.; Ross L. Stein.; Jonathan M.G. Higgins. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors.Bioorg Med Chem Lett.2010,20(12), 3491-3494.

Xingju Jin.; Xinge Zhang.; Zhongming Wu.; Dayong Teng.; Xuejiao Zhang.; Yanxia Wang.; Zhen Wang.; Chaoxing Li. Amphiphilic random glycopolymer based on phenylboronic acid: synthesis, characterization, and potential as glucose-sensitive matrix.Biomacromolecules.2009,10(6), 1337-1345.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319

Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313

Wear protective gloves and eye/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists:

Other References

Beilstein
2936342
Harmonized Tariff Code
2931.90
TSCA
No

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