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It is employed as a reagent in the preparation of Suzuki-Miyaura cross-coupling, used for Gram-positive ant virulence drugs and inhibitors of Streptococcus agalactiae Stk1, regioisomer of Zaleplon (a sedative), amphiphilic random glycopolymer, which self-assemble to form nanoparticles, with potential as a glucose-sensitive matrix, chemomechanical polymer that expands and contracts in blood plasma with high glucose selectivity. Aminophenylboronic Acid is also used as a reagent in the preparation of nonbenzodiazepine hypnotic agents.
Gregory D. Cuny.; Maxime Robin.; Natalia P. Ulyanova.; Debasis Patnaik.; Valerie Pique.; Gilles Casano.; Ji-Feng Liu.; Xiangjie Lin.; Jun Xian.; Marcie A. Glicksman.; Ross L. Stein.; Jonathan M.G. Higgins. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors.Bioorg Med Chem Lett.2010,20(12), 3491-3494.
Xingju Jin.; Xinge Zhang.; Zhongming Wu.; Dayong Teng.; Xuejiao Zhang.; Yanxia Wang.; Zhen Wang.; Chaoxing Li. Amphiphilic random glycopolymer based on phenylboronic acid: synthesis, characterization, and potential as glucose-sensitive matrix.Biomacromolecules.2009,10(6), 1337-1345.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant