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2,2,5,5-Tetramethyl-3-pyrroline-3-carboxamide may be used in the synthesis of 2,2,5,5-tetramethyl-3-pyrrolidinecarboxamide and 3-carbamoyl-2,2,5,5-tetramethyl-3-pyrrolin-1-yloxy free radical.
Ravi A.Shankar; Kalman Hideg; Jay L.Zweier; Periannan Kuppusamy. Targeted antioxidant properties ofN-[(Tetramethyl-3-pyrroline-3-carboxamido) propyl] phthalimide and its nitroxide metabolite in preventing postischemic myocardial injury. JPET. 2000, 292,(3), 838-845.
Karen Wright; Laurence Dutot; Michel Wakselman; Jean-Paul Mazaleyrat, Marco Crisma, Fernando Formaggio, Claudio Toniolo. Synthesis, resolution and assignment of absolute configuration of trans 3-amino-1-oxyl-2,2,5,5-tetramethylpyrrolidine-4-carboxylic acid (POAC), a cyclic, spin-labelled β-amino acid. Tetrahedron. 2008, 64,(19), 4416-4426.