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A18308 5-Chloro-1-indanone, 99%

CAS Number
42348-86-7
Synonyms

Stock No. Size Price ($) Quantity Availability
A18308-03 1g 43.80
A18308-06 5g 144.00
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5-Chloro-1-indanone, 99%

MDL
MFCD00041456

Chemical Properties

Formula
C9H7ClO
Formula Weight
166.61
Melting point
92-96°
Boiling Point
124-125°/3mm
Storage & Sensitivity
Ambient temperatures.
Solubility
Insoluble in water.

Applications

5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.

Notes

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Literature References

Mark T. DuPriest; Charles L.Schmidt; Daniel Kuzmich; Stanly B.Williams. A facile synthesis of 7-halo-5H-indeno[1,2-b]pyridines and -pyridin-5-ones. J. Org. Chem. 1986, 51,(11), 2021-2023.

 

Tomas Pena Ruiz; Manuel Fernandez Gomez; Juan Jesus Lopez Gonzalez; Anna E.Koziol. Weak hydrogen-, halogen- and stacking π?π bonding in crystalline 5-chloro-1-indanone. An analysis by using X-ray diffraction, vibrational spectroscopy and theoretical methods. Chemical Physics. 2006, 320,(2-3), 164-180.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1448000
Harmonized Tariff Code
2914.79
TSCA
Yes

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