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A18329 4-(Trifluoromethyl)aniline hydrochloride, 97%

CAS Number
4-Aminobenzotrifluoride hydrochloride

Stock No. Size Price ($) Quantity Availability
A18329-06 5g 47.30
A18329-14 25g 151.00
A18329-22 100g 502.00
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4-(Trifluoromethyl)aniline hydrochloride, 97%


Chemical Properties

Formula Weight
Melting point
ca 240° dec.
Storage & Sensitivity
Ambient temperatures.


4-(Trifluoromethyl)aniline hydrochloride is used in the synthesis of 2-(4-((6-Chloro-2-quinoxalinyl)oxy)phenoxy)-N-(4-(trifluoromethyl)phenyl)propanamide. It is also used to produce N-(p-trifluoromethylphenyl)phosphoramidic dichloride.


Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents. It is hygroscopic in nature.

Literature References

Chun-Yen Chen.; Hui-Chang Lin.; Yu-Ying Huang.; Kun-Lung Chend.; Jiann-Jyh Huang.; Mou-Yung Yeh.; Fung Fuh Wong. ‘One-flask’ transformation of isocyanates and isothiocyanates to guanidines hydrochloride by using sodium bis(trimethylsilyl)amide. Tetrahedron. 2010, 66 (10), 1892-1897.

Thomas-Xavier Métro.; Julien Bonnamour.; Thomas Reidon.; Jordi Sarpoulet.; Jean Martineza.; Frédéric Lamaty. Mechanosynthesis of amides in the total absence of organic solvent from reaction to product recovery. Chem. Commun. 2012, 48 (96), 11781-11783.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H312-H315-H319-H332-H335-H373

Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. Harmful if inhaled. May cause respiratory irritation. May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements: P260-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P314-P330-P332+P313-P337+P313-P362-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Hazard Class
Packing Group
Harmonized Tariff Code


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