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A18373 1-(2-Aminoethyl)piperidine, 98%

CAS Number
27578-60-5
Synonyms
1-Piperidineethylamine
2-(1-Piperidinyl)ethylamine

Stock No. Size Price ($) Quantity Availability
A18373-06 5g 38.80
A18373-14 25g 129.00
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1-(2-Aminoethyl)piperidine, 98%

MDL
MFCD00006516
EINECS
248-540-8

Chemical Properties

Formula
C7H16N2
Formula Weight
128.22
Boiling Point
185-186°
Flash Point
57°(134°F)
Density
0.903
Refractive Index
1.4740
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Solubility
Partly miscible in water.

Applications

1-(2-Aminoethyl)piperidine is used in modification of vinylbenzyl chloride/divinylbenzene gel copolymer bead and in the synthesis of linkage isomers trans-bis[1-(2-aminoethyl)piperidine]dinitronickel and trans-bis[1-(2-aminoethyl)-piperidine]dinitritonickel. It is also used as a reactant for synthesis of: analogs of anticancer agents, inhibitor of botulinum neurotoxin serotype A light chain, P. falciparum malaria, and Ebola filovirus, cannabinoid CB1 receptor antagonists, small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells, potent and selective 5-HT6 antagonists and N-mustards as anticancer agents. 1-(2-Aminoethyl)piperidine on [1+1] condensation reaction with 3-methoxy salicylaldehyde yields tridentate Schiff base ligand.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents, acid chlorides and acid anhydrides. It is sensitive to air.

Literature References

Dorota Jermakowicz-Bartkowiak. Polymer resins for recovery of valuable metals. Environmental Geochemistry and Health. 2010, 32 (4), 317-320.

Sujit Sasmal.; Sohini Sarkar.; Núria Aliaga-Alcalde.; Sasankasekhar Mohanta. Syntheses, structures, and magnetic properties of three one-dimensional end-to-end azide/cyanate-bridged copper(II) compounds exhibiting ferromagnetic interaction: new type of solid state isomerism. Inorganic Chemistry. 2011, 50 (12), 5687-5695.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H314

Flammable liquid and vapour. Causes severe skin burns and eye damage.

Precautionary Statements: P210-P233-P240-P241-P242-P243-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
103469
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2933.39
TSCA
No

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