Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A18413 5-Iodo-m-xylene, 97%

CAS Number
22445-41-6
Synonyms
1,3-Dimethyl-5-iodobenzene
1-Iodo-3,5-dimethylbenzene

Stock No. Size Price ($) Quantity Availability
A18413-09 10g 43.40
A18413-18 50g 150.00
Add to Cart Bulk/Specialty Print Quote View Item

5-Iodo-m-xylene, 97%

MDL
MFCD00060659
EINECS
000-000-0

Chemical Properties

Formula
C8H9I
Formula Weight
232.07
Boiling Point
229°
Flash Point
>110°(230°F)
Density
1.610
Refractive Index
1.5950
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Sparingly soluble (0.014 g/L) (25°C), Calc.

Applications

1-Iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is suitable for use in the synthesis of N-(3,5-xylyl)-N-ethyl aniline, an aryl amine, It is also used in the following studies; α-Arylation of ketones, Copper-catalyzed N-arylation of imidazoles, Cyanation of 5-iodo-m-xylene to form 3,5-dimethylbenzonitrile, synthesis of 1,3-Dimethyl-5-phenoxybenzene by nano-CuFe2O4 catalyzed C-O cross-coupling with phenol, CuBr-catalyzed amination of 1-iodo-3,5-dimethylbenzene to form N-Allyl-3,5-dimethylbenzenamine, copper-catalyzed C-S bond-formation between 5-iodo-m-xylene and thiophenol. It is also employed as a starting material in the synthesis of biphenyl-3,3’,5,5’-tetracarboxylic acid, radical bromination of 5-iodo-m-xylene by N-bromosuccinimide to form 1,3-bis(bromomethyl)-5-iodobenzene.

Notes

Light Sensitive. Store away from oxidizing agents and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

M H Ali.; S L Buchwald. An improved method for the palladium-catalyzed amination of aryl iodides. Org Chem.2001,66(8), 2560-2565.

Anouk S Lubbe, et. al. Control of rotor function in light-driven molecular motors.J. Org Chem.2011,76(21), 8599-8610.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2039353
Harmonized Tariff Code
2903.99
TSCA
No

Recommended

  • A10280

    Diisopropylamine, 99+%
  • A11930

    Thiophene-2-carbonitrile, 98%
  • A16874

    Ferrocenecarboxylic acid, 98%
  • B23244

    Bathophenanthrolinedisulfonic acid disodium salt hydrate, 98%
  • B23532

    2-Ethylhexyl bromide, 96%, stab. with copper

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware