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A18494 Tris(hydroxymethyl)aminomethane, 99%

CAS Number
77-86-1
Synonyms
2-Amino-2-hydroxymethyl-1,3-propanediol
TRIS

Stock No. Size Price ($) Quantity Availability
A18494-22 100g 25.50
A18494-36 500g 52.60
A18494-0E 2500g 173.00
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Tris(hydroxymethyl)aminomethane, 99%

MDL
MFCD00004679
EINECS
201-064-4

Chemical Properties

Formula
C4H11NO3
Formula Weight
121.14
Melting point
168-172°
Boiling Point
219-220°/10mm
Density
1.353
Storage & Sensitivity
Hygroscopic. Ambient temperatures.
Solubility
Soluble in water, ethylene glycol, methanol, ethanol,dimethyl formamide, acetone, ethyl acetate, olive oil, chloroform and alkaline solution.

Applications

Tris(hydroxymethyl)aminomethane is used as buffers in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase its permeability. As an alternative to sodium bicarbonate, it used in the treatment of metabolic acidosis.

Notes

Hygroscopic. Incompatible with bases and strong oxidizing agents.

Literature References

Widely used biological buffer.

Filipiak, M. S.; Zloczewska, A.; Grzeskowiak, P.; Lynch, R.; Niedziolka, M. J. Tris (hydroxymethyl) aminomethane photooxidation on titania based photoanodes and its implication for photoelectrochemical biofuel cells. J. Power Sources 2015, 289, 17-21.

Lee, S. M.; Sim, K. S.; Lo, K. M. Synthesis, characterization and biological studies of diorganotin (IV) complexes with tris [(hydroxymethyl) aminomethane] Schiff bases. Inorg. Chim. Acta 2015, 429, 195-208.

Other References

Merck
14,9772
Beilstein
741883
Harmonized Tariff Code
2922.19
TSCA
Yes
RTECS
TY2900000

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