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A18680 Sulfamide, 99%

CAS Number
7803-58-9
Synonyms

Stock No. Size Price ($) Quantity Availability
A18680-88 2.5g 43.10
A18680-09 10g 92.50
A18680-18 50g 311.00
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Sulfamide, 99%

MDL
MFCD00011606
EINECS
232-262-9

Chemical Properties

Formula
SO2(NH2)2
Formula Weight
96.11
Melting point
91-92°
Density
1.61
Storage & Sensitivity
Moisture Sensitive. Ambient temperatures.
Solubility
Soluble in water, hot alcohol, acetone. Sparingly soluble in cold alcohol

Applications

It is employed as a carbonic anhydrase inhibitor. It is widely used as a pharmaceutical intermediate.

Notes

Moisture Sensitive. Store away from oxidizing agents, water/humidity. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Deborah Sterling.; Reinhart A. F. Reithmeier.; and Joseph R. Casey. A Transport Metabolon. Functional Interaction Of Carbonic Anhydrase Ii And Chloride/Bicarbonate Exchangers. J. Bio. Chem.,2001,27647886-47894.

Maryanoff BE.; McComsey DF.; Costanzo MJ.; Hochman C.; Smith-Swintosky V.; Shank RP. Comparison of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-II by using topiramate as a structural platform.J Med Chem.2005,48(6), 1941-1947.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335-H500

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May form combustible dust concentrations in air

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,8922
Harmonized Tariff Code
2853.90
TSCA
Yes

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