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It is employed as a carbonic anhydrase inhibitor. It is widely used as a pharmaceutical intermediate.
Deborah Sterling.; Reinhart A. F. Reithmeier.; and Joseph R. Casey. A Transport Metabolon. Functional Interaction Of Carbonic Anhydrase Ii And Chloride/Bicarbonate Exchangers. J. Bio. Chem.,2001,27647886-47894.
Maryanoff BE.; McComsey DF.; Costanzo MJ.; Hochman C.; Smith-Swintosky V.; Shank RP. Comparison of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-II by using topiramate as a structural platform.J Med Chem.2005,48(6), 1941-1947.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.