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It is employed as a carbonic anhydrase inhibitor. It is widely used as a pharmaceutical intermediate.
Deborah Sterling.; Reinhart A. F. Reithmeier.; and Joseph R. Casey. A Transport Metabolon. Functional Interaction Of Carbonic Anhydrase Ii And Chloride/Bicarbonate Exchangers. J. Bio. Chem.,2001,27647886-47894.
Maryanoff BE.; McComsey DF.; Costanzo MJ.; Hochman C.; Smith-Swintosky V.; Shank RP. Comparison of sulfamate and sulfamide groups for the inhibition of carbonic anhydrase-II by using topiramate as a structural platform.J Med Chem.2005,48(6), 1941-1947.
Hazard Statements: H315-H319-H335-H500
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May form combustible dust concentrations in air
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant