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5392-28-9 - 2,4,5,6-Tetraaminopyrimidine sulfate, 97% - A18788 - Alfa Aesar

A18788 2,4,5,6-Tetraaminopyrimidine sulfate, 97%

CAS Number
5392-28-9
Synonyms

Size Price ($) Quantity Availability
10g 20.12
50g 69.32
250g 240.80
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2,4,5,6-Tetraaminopyrimidine sulfate, 97%

MDL
MFCD00012786
EINECS
226-393-0

Chemical Properties

Formula
C4H8N6•H2SO4
Formula Weight
238.23
Melting point
>300°
Solubility
Soluble in water and dimethyl sulfoxide.

Applications

Used as an intermediate in the production of Methotrexate.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

Chiosis G; Lucas B; Shtil A; Huezo H; Rosen N. Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase. Bioorg Med Chem., 2002, 10 (11), 3555-64.

Palanki, M., et al. Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction. J. Med. Chem., 2007, 50(18), 4279-4294.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3785189
Harmonized Tariff Code
2933.59
TSCA
Yes

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