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It finds its uses as an antimalarial compound. It is a lysosomotropic agent, inhibits Plasmodium falciparum, interferes with ferriprotoporphyrin formation and is a weak SERT inhibitor.
Barennes H.; Verdier F.; Clavier F.; Pussard E. Pharmacokinetics of Quinimax suppositories in children with malaria: preliminary study.Clin. Drug Invest.;1999,17287-291.
J M Karle.; I L Karle.; L Gerena and W K Milhous Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum.Antimicrob. Agents Chemother.1992,36(7), 1538-1544.
Hazard Statements: H302-H334-H317
Harmful if swallowed. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary Statements: P284-P261-P280g-P342+P311a-P301+P312a-P501a
Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Dispose of contents/container in accordance with local/regional/national/international regulations.