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106-57-0 - Glycine anhydride, 99% - 2,5-Piperazinedione - 2,5-Diketopiperazine - A18822 - Alfa Aesar

A18822 Glycine anhydride, 99%

CAS Number
106-57-0
Synonyms
2,5-Piperazinedione
2,5-Diketopiperazine

Size Price ($) Quantity Availability
25g 42.75
100g 121.95
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Glycine anhydride, 99%

MDL
MFCD00006009
EINECS
203-411-5

Chemical Properties

Formula
C4H6N2O2
Formula Weight
114.10
Melting point
ca 300° dec.
Solubility
Soluble in water (142mg/L).

Applications

It can be used as an intermediate in the preparation of various pharmaceutical and biologically active compounds. Also used in the synthesis of dipeptide isosteres by cross-metathesis.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Literature References

A K Szardenings; D Harris; S Lam; L Shi, D Tien; Y Wang; D V Patel; M Navre; D A Campbell. Rational design and combinatorial evaluation of enzyme inhibitor scaffolds: identification of novel inhibitors of matrix metalloproteinases. Journal of Medicinal Chemistry, 1998, 41 (13), 2194-2200.

Da Wang et. al. Diagnostic NH and OH vibrations for oxazolone and diketopiperazine structures: b2 from protonated triglycine. Journal of the American Society for Mass Spectrometry, 2011, 22(7), 1197-1203.

Other References

Merck
14,7466
Beilstein
112112
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
TL6325250

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