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A18912 Thionin acetate

CAS Number
78338-22-4
Synonyms

Stock No. Size Price ($) Quantity Availability
A18912-06 5g 49.60
A18912-14 25g 147.00
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Thionin acetate

MDL
MFCD00081194

Chemical Properties

Formula
C14H13N3O2S
Formula Weight
287.34
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water (~2.5 mg/ml at 25°C), and HOAc: H2O (1:1) (1 mg/ml). Insoluble in ethanol.

Applications

Thionin acetate is a strongly staining metachromatic dye that is widely used for biological staining. Thionine can also be used in place of Schiff reagent in quantitative Feulgen staining of DNA. It can also be used to mediate electron transfer in microbial fuel cells. It is also employed as a general nuclear stain for chromatin and mucin; for staining Nissl granules by end-point buffering and for showing malignant cells in frozen biopsy sections; and as a stain for semi-thin sections of plant material for light microscopy.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Huang W.; Vernon LP.; Bell JD. Enhancement of adenylate cyclase activity in S49 lymphoma cell membranes by the toxin thionin from Pyrularia pubera.Toxicon.1994,32(7), 789-97.

D P Penney.; J M Powers.; M Frank.; C Willis.; C Churukian. Analysis and testing of biological stains--the Biological Stain Commission Procedures.Biotech Histochem.2002,77(5-6), 237-275.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Harmonized Tariff Code
2934.30
TSCA
No

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