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A18930 5,8-Dihydroxy-1,4-naphthoquinone, 97%

CAS Number
475-38-7
Synonyms
Naphthazarin

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Bulk/Specialty

5,8-Dihydroxy-1,4-naphthoquinone, 97%

MDL
MFCD00001685
EINECS
207-495-4

Chemical Properties

Formula
C10H6O4
Formula Weight
190.16
Melting point
ca 230° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water (5520 mg/L 25.).

Applications

It finds its application as a substance used to destroy pests of the subclass Acari (mites and ticks). It is also employed as a substance that inhibits or prevents the proliferation of neoplasms. It also has a biological role as a substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Carreño MC.; García Ruano JL.; Urbano A. Remote Regiocontrol by a Thioether Group in Diels-Alder Reactions of Naphthazarin: Regioselective Access to Tetracyclic Polyhydroxyquinones.J Org. Chem.1996,61(18), 6136-6138.

Kim JA.; Lee EK.; Park SJ.; Kim ND.; Hyun DH.; Lee CG.; Lee JH.; Yang KM.; Heo K.; Son TG. Novel anti-cancer role of naphthazarin in human gastric cancer cells.Int. J. Oncol.2012,40(1), 157-162.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
880561
Harmonized Tariff Code
2914.69
TSCA
No
RTECS
QL7970000

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