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A18994 5-Iodouracil, 97%

CAS Number
696-07-1
Synonyms

Stock No. Size Price ($) Quantity Availability
A18994-09 10g 39.80
A18994-18 50g 146.00
A18994-30 250g 610.00
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5-Iodouracil, 97%

MDL
MFCD00006020
EINECS
211-788-2

Chemical Properties

Formula
C4H3IN2O2
Formula Weight
237.99
Melting point
274-276°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Very faint turbidity in NH3aq. Soluble in 1M NaOH.

Applications

It is used as an intermediate. It has an antitumor activity.

Notes

Light Sensitive. Store away from oxidizing agents and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Morris J. Robins.; Philip J. Barr.Nucleic acid related compounds. 31. Smooth and efficient palladium-copper catalyzed coupling of terminal alkynes with 5-iodouracil nucleosides.Tetrahedron Lett.198122(5), 421-424.

MC Willis.; BJ Hicke.; OC Uhlenbeck.; TR Cech.; TH Koch. Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins.Science.1993,262(5137), 1255-1257.

For a review of the use of uracils as starting materials in heterocyclic synthesis, see: Adv. Het. Chem., 55, 130 (1992).

GHS Hazard and Precautionary Statements

Hazard Statements: H302+H312+H332-H315-H319-H335

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
4891
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
YR0525000

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