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696-07-1 - 5-Iodouracil, 97% - A18994 - Alfa Aesar

A18994 5-Iodouracil, 97%

CAS Number
696-07-1
Synonyms

Size Price ($) Quantity Availability
10g 37.10
50g 139.00
250g 592.00
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5-Iodouracil, 97%

MDL
MFCD00006020
EINECS
211-788-2

Chemical Properties

Formula
C4H3IN2O2
Formula Weight
237.99
Melting point
274-276°
Sensitivity
Light Sensitive
Solubility
Very faint turbidity in NH3aq. Soluble in 1M NaOH.

Applications

It is used as an intermediate. It has an antitumor activity.

Notes

Light Sensitive. Store away from oxidizing agents and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Morris J. Robins.; Philip J. Barr.Nucleic acid related compounds. 31. Smooth and efficient palladium-copper catalyzed coupling of terminal alkynes with 5-iodouracil nucleosides.Tetrahedron Lett.198122(5), 421-424.

MC Willis.; BJ Hicke.; OC Uhlenbeck.; TR Cech.; TH Koch. Photocrosslinking of 5-iodouracil-substituted RNA and DNA to proteins.Science.1993,262(5137), 1255-1257.

For a review of the use of uracils as starting materials in heterocyclic synthesis, see: Adv. Het. Chem., 55, 130 (1992).

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
4891
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
YR0525000

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