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Thiamine hydrochloride plays an important role as a nutrient for carbohydrate metabolism and in nerve function. It finds application as a food-additive to add a brothy/meaty flavor to gravies or soups. It is involved in the preparation of 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazolium chloride. In addition, it finds use in amino acid synthesis in cultured cells, which is present in many classical and serum-free formulations.
Yan, X.; Li, S.; Pan, Y. X.; Yang, Z.; Liu, X. A simple approach to the synthesis of Cu1. 8S dendrites with thiamine hydrochloride as a sulfur source and structure-directing agent. Beilstein J. Nanotechnol. 2015, 6 (1), 881-885.
Sarker, S.; Tammi, R. S.; Biswas, S.; Zaman, S.; Seraj, Z. I. Cloning and Characterization of a Tissue Specific Promoter GluB-1 from Nipponbare by Transformation in Rice(Vitamin-B1) Application. Biores Comm. 2015, 1 (2), 69-75.
Hazard Statements: H303-H315-H319-H335
May be harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.