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3,5-Dichlorophenyl isocyanate is used as an intermediate for medicine and in iprodione. It is also useful for proteomic research.
Singhal, S. S.; Figarol, J.; Singhal, J.; Nagaprashanth, L. N.; Berz, D.; Rahbar, S.; Awasthi, S. Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung cancer progression. Biochem. Pharmacol. 2013, 86 (12), 1664-1672.
Uraguchi, D.; Tsutsumi, R.; Ooi, T. Catalytic Asymmetric Oxidation of N-Sulfonyl Imines with Hydrogen Peroxide-Trichloroacetonitrile System. J. Am. Chem. Soc. 2013, 135 (22), 8161-8164.
Johnson, A.; Saundersa, M. J.; Back, T. G. Stereodivergent synthesis of the LFA-1 antagonist BIRT-377 by porcine liver esterase desymmetrization and Curtius rearrangement. Org. Biomol. Chem. 2015, 13 (5), 1463-1469.
Hazard Statements: H311-H315-H319-H331-H334-H335
Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation. Toxic if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P285-P302+P352-P304+P340-P305+P351+P338-P311-P312-P332+P313-P337+P313-P361-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant