Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A19992 2,3-Dimethylanisole, 97%

CAS Number
2944-49-2
Synonyms
3-Methoxy-o-xylene

Stock No. Size Price ($) Quantity Availability
A19992-09 10g 43.00
A19992-18 50g 128.00
Add to Cart Bulk/Specialty Print Quote View Item

2,3-Dimethylanisole, 97%

MDL
MFCD00008376
EINECS
220-948-0

Chemical Properties

Formula
C9H12O
Formula Weight
136.19
Melting point
29°
Boiling Point
195°
Flash Point
67°(152°F)
Density
0.984
Refractive Index
1.5200
Storage & Sensitivity
Ambient temperatures.
Solubility
Not miscible or difficult to mix in water.

Applications

2,3-Dimethylanisole is used as starting reagent in the synthesis of biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2. It can be used to produce 2-methoxy-6-methyl-benzaldehyde by heating.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Goldberg Y, et al. Highly regioselective bromination of 2, 3-dimethylanisole with N-bromosuccinimide.J. Org. Chem.1992,57(23), 6374-6376.

Ruggero Galici, et al. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.J Pharmacol Exp Ther.2006,318(1),173-185.

Methyl groups o- or p- to alkoxy groups can be selectively oxidized to the aldehyde by potassium peroxydisulfate in the presence of Cu(II): Synthesis, 723 (1987).

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H315-H319

Combustible liquid. Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P210-P235-P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1859736
Harmonized Tariff Code
2909.30
TSCA
No

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware