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83-44-3 - Deoxycholic acid, 99% - B20061 - Alfa Aesar

B20061 Deoxycholic acid, 99%

CAS Number
83-44-3
Synonyms

Size Price ($) Quantity Availability
25g 23.69
100g 51.50
500g 203.94
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Deoxycholic acid, 99%

MDL
MFCD00003673
EINECS
201-478-5

Chemical Properties

Formula
C24H40O4
Formula Weight
392.58
Melting point
172-176°
Solubility
The free acid is soluble at 0.044 g/L in water at 20°C. Solubility in methanol is almost transparent.

Applications

Deoxycholic acid has been used in a modified procedure to recover 40-80% of a protein from a 1 µg/mL solution. It forms complexes with fatty acid. Used as an emulsifying agent in food, a precursor in the synthesis of cortisone, and a gallbladder stimulant. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue. Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Patricia Martínez-Moya, et al. Dose-dependent antiinflammatory effect of ursodeoxycholic acid in experimental colitis.Int Immunopharmacol.2013,15(2),372-380.

Kuen Yong Lee and Won Ho Jo.Structural Determination and Interior Polarity of Self-Aggregates Prepared from Deoxycholic Acid-Modified Chitosan in Water.Macromolecules,1998,31(2), 378-383.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2899
Beilstein
3219882
Harmonized Tariff Code
2918.19
TSCA
Yes
RTECS
FZ2100000

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