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Periodic acid is used as a component for glycoprotein stains. It serves as a pharmaceutical and synthetic intermediate and is used in silk screen printing. It acts as an oxidizing agent especially in the cleavage of 1,2 diols to prepare dialdehydes. It has selective oxidation powers which makes it an ideal reagent for the reclamation of silk screens in the printing industry. It finds application in life sciences for the analysis of intracellular polysaccharides like glycogen, starch and cellulose. Furthermore, it is used in oxidation reactions converting sulfides into sulfones, catalyzed by chromium(VI) oxide and oxidation reactions converting alcohols to aldehydes and ketones.
Oxidizing agent. For reactions of periodate ion, see Sodium metaperiodate, 13798. Reagent for deblocking of dithioacetal and oxathioacetal protecting groups under mild, non-aqueous conditions in THF-ether: Tetrahedron Lett., 37, 4331 (1996). Stoichiometric oxidant used in combination with catalytic Chromium(VI) oxide, 12522, for conversion of alcohols to carboxylic acids in wet acetonitrile: Tetrahedron Lett., 39, 5323 (1998).
Yang, Z.; Sun, B.; Zhao, X.; Shao, B.; An, J.; Gu, Q.; Wang, Y.; Dong, X.; Zhang, Y.; Qiu, Z. Erythropoietin and erythropoietin receptor in hepatocellular carcinoma: correlation with vasculogenic mimicry and poor prognosis. Int J Clin Exp Pathol 2015, 8 (4), 4033-4043.
Jarrett, B. R.; Gustafsson, B.; Kukis, D. L.; Louie, A. Y. Synthesis of 64Cu-labeled magnetic nanoparticles for multimodal imaging. Bioconjugate Chem. 2008, 19 (7), 1496-1504.
Hazard Statements: H271-H314-H335-H372
May cause fire or explosion; strong oxidizer. Causes severe skin burns and eye damage. May cause respiratory irritation. Causes damage to organs through prolonged or repeated exposure.
Precautionary Statements: P210-P220-P221-P260-P264b-P270-P271-P280-P283-P301+P330+P331-P304+P340-P305+P351+P338-P306+P360-P310-P353-P363-P370+P378q-P371+P380+P375-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep/Store away from clothing/combustible materials. Take any precaution to avoid mixing with combustibles. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Wear fire/flame resistant/retardant clothing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF ON CLOTHING: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes. Immediately call a POISON CENTER or doctor/physician. Rinse skin with water/shower. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion. Dispose of contents/ container to an approved waste disposal plant