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10450-60-9 - Periodic acid, 99% - B20433 - Alfa Aesar

B20433 Periodic acid, 99%

CAS Number

Size Price ($) Quantity Availability
50g 46.80
250g 136.00
1000g 456.00
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Periodic acid, 99%


Chemical Properties

Formula Weight
Melting point
Light Sensitive & Hygroscopic
Soluble in water and alcohols.


Periodic acid is used as a component for glycoprotein stains. It serves as a pharmaceutical and synthetic intermediate and is used in silk screen printing. It acts as an oxidizing agent especially in the cleavage of 1,2 diols to prepare dialdehydes. It has selective oxidation powers which makes it an ideal reagent for the reclamation of silk screens in the printing industry. It finds application in life sciences for the analysis of intracellular polysaccharides like glycogen, starch and cellulose. Furthermore, it is used in oxidation reactions converting sulfides into sulfones, catalyzed by chromium(VI) oxide and oxidation reactions converting alcohols to aldehydes and ketones.


Light sensitive and hygroscopic. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong reducing agents, powdered metals, strong bases and dimethyl sulfoxide.

Literature References

Oxidizing agent. For reactions of periodate ion, see Sodium metaperiodate, 13798. Reagent for deblocking of dithioacetal and oxathioacetal protecting groups under mild, non-aqueous conditions in THF-ether: Tetrahedron Lett., 37, 4331 (1996). Stoichiometric oxidant used in combination with catalytic Chromium(VI)­ oxide, 12522, for conversion of alcohols to carboxylic acids in wet acetonitrile: Tetrahedron Lett., 39, 5323 (1998).

Yang, Z.; Sun, B.; Zhao, X.; Shao, B.; An, J.; Gu, Q.; Wang, Y.; Dong, X.; Zhang, Y.; Qiu, Z. Erythropoietin and erythropoietin receptor in hepatocellular carcinoma: correlation with vasculogenic mimicry and poor prognosis. Int J Clin Exp Pathol 2015, 8 (4), 4033-4043.

Jarrett, B. R.; Gustafsson, B.; Kukis, D. L.; Louie, A. Y. Synthesis of 64Cu-labeled magnetic nanoparticles for multimodal imaging. Bioconjugate Chem. 2008, 19 (7), 1496-1504.

GHS Hazard and Precautionary Statements

Hazard Statements: H272-H314

May intensify fire; oxidizer. Causes severe skin burns and eye damage.

Precautionary Statements: P221-P210v-P303+P361+P353-P305+P351+P338-P405-P501a

Take any precaution to avoid mixing with combustibles. Keep away from heat IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

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Packing Group
Harmonized Tariff Code


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