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3250-74-6 - 5-(3-Pyridyl)-1H-tetrazole, 98% - 3-[1(2)H-Tetrazol-5-yl]pyridine - B20492 - Alfa Aesar

B20492 5-(3-Pyridyl)-1H-tetrazole, 98%

CAS Number
3250-74-6
Synonyms
3-[1(2)H-Tetrazol-5-yl]pyridine

Size Price ($) Quantity Availability
1g 65.12
5g 336.81
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5-(3-Pyridyl)-1H-tetrazole, 98%

MDL
MFCD00040281
EINECS
426-810-8

Chemical Properties

Formula
C6H5N5
Formula Weight
147.14
Melting point
ca 240° dec.
Solubility
Soluble in water (slightly).

Applications

5-(3-Pyridyl)-1H-tetrazole is used as a pharmaceutical intermediate. The Pyridine,3-(2H-tetrazol-5-yl)- acts as reactant with 1-(4-bromo-phenyl)-3-piperidino-propan-1-one, hydrochloride, and obtain the 1-(4-bromo-phenyl)-3-(5-pyridin-3-yl-tetrazol-2-yl)-propan-1-one. This reaction needs the solvent of dimethylformamide. The yield is 31%. In addition, this reaction should be taken for 8 hours at the temperature of 150°C.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Literature References

H X Xue.; XS Wang.; LZ Wang.; RG Xiong. Hydrothermal preparation of novel Cd (II) coordination polymers employing 5-(4-pyridyl) tetrazolate as a bridging ligand. Inorg. Chem. 200241 ( 25), 6544-6546.

EK Moltzen.; H Pedersen.; KP Boegesoe. Bioisosteres of Arecoline: 1,2,3,6-Tetrahydro-5-pyridyl-Substituted and 3-Piperidyl-Substituted Derivatives of Tetrazoles and 1,2,3-Triazoles. Synthesis and Muscarinic Activity. J. Med. Chem. 199437 ( 24), 4085-4099.

GHS Hazard and Precautionary Statements

Hazard Statements: H318

Causes serious eye damage.

Precautionary Statements: P280d-P305+P351+P338

Wear protective clothing and eye protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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