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o-Toluene sulfonamide was mainly produced as a chemical intermediate for the production of saccharin. A mixture of o-Toluene sulfonamide with the p-isomer is used as a plasticizer for hot -melt adhesives, a chemical intermediate for fluorescent pigments and a chemical intermediate for plasticizer resins. (S080800). Studies suggest that o-Toluene sulfonamide has potential mutagenic activity.
JL Kacprzak. Determination of o-toluenesulfonamide in artificial sweeteners containing saccharin. Journal-Association of Official Analytical Chemists. 197861 (6), 1528-1532.
L Xu.; H Shu.; Y Liu.; S Zhang.; ML Trudell. Oxidative cyclization of N-alkyl-o-methyl-arenesulfonamides to biologically important saccharin derivatives. Tetrahedron. 200661 (6), 1528-1532.
Hazard Statements: H351
Suspected of causing cancer.
Precautionary Statements: P201-P202-P281-P308+P313-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant