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146-56-5 - Fluphenazine dihydrochloride, 98% - B20848 - Alfa Aesar

B20848 Fluphenazine dihydrochloride, 98%

CAS Number
146-56-5
Synonyms

Size Price ($) Quantity Availability
25g 44.91
100g 130.81
500g 333.60
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Fluphenazine dihydrochloride, 98%

MDL
MFCD00055212
EINECS
205-674-1

Chemical Properties

Formula
C22H26F3N3OS•2HCl
Formula Weight
510.44
Sensitivity
Hygroscopic
Solubility
Soluble in DMSO and methanol.

Applications

It is employed as a dopamine D1 receptor antagonist and a D1DR and D2DR inhibitor. Fluphenazine Dihydrochloride has been used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist. It is also employed as an antipsychotic.

Notes

Hygroscopic. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas.

Literature References

G Cai, et al. Inverse agonist properties of dopaminergic antagonists at the D(1A) dopamine receptor: uncoupling of the D(1A) dopamine receptor from G(s) protein.Mol Pharmacol.199956(5), 989-996.

Trzeciak HI, et al. Behavioral effects of withdrawal of fluphenazine after long-term treatment. Arzneimittelforschung.1976,26(9), 1697-700.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2934.30
TSCA
No

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