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It is primarily used an intermediate in the manufacture of pharmaceutical and agrochemical products. Methyl cyclopropane carboxylate is used as a reagent in the synthesis of N-thiazole and N-pyrazole based inhibitors of MAP kinase p38α.
Matthäus Getlik, et al. Structure-based design, synthesis and biological evaluation of N-pyrazole, N?-thiazole urea inhibitors of MAP kinase p38α.Eur. J. Med. Chem.2012481-15.
Roseann Kroeker Sachs, et al. 3-Carbomethoxycyclopropen-3-yl Anion. Formation and Characterization of an Antiaromatic Ion. J. Am. Chem. Soc.,1994,116(2), 783-784.
Hazard Statements: H225-H302-H331-H319
Highly flammable liquid and vapour. Harmful if swallowed. Toxic if inhaled. Causes serious eye irritation.
Precautionary Statements: P260-P201-P280a-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves and eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.