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2868-37-3 - Methyl cyclopropanecarboxylate, 98% - Cyclopropanecarboxylic acid methyl ester - B20853 - Alfa Aesar

B20853 Methyl cyclopropanecarboxylate, 98%

CAS Number
2868-37-3
Synonyms
Cyclopropanecarboxylic acid methyl ester

Size Price ($) Quantity Availability
25g 21.12
100g 62.11
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Methyl cyclopropanecarboxylate, 98%

MDL
MFCD00001280
EINECS
220-690-9

Chemical Properties

Formula
C5H8O2
Formula Weight
100.12
Boiling Point
118-119°
Flash Point
22°(71°F)
Density
0.983
Refractive Index
1.4180
Solubility
Not miscible or difficult to mix in water.

Applications

It is primarily used an intermediate in the manufacture of pharmaceutical and agrochemical products. Methyl cyclopropane carboxylate is used as a reagent in the synthesis of N’-thiazole and N-pyrazole based inhibitors of MAP kinase p38α.

Notes

Store away from oxidizing agents and ignition sources. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from electrostatic charges.

Literature References

Matthäus Getlik, et al. Structure-based design, synthesis and biological evaluation of N-pyrazole, N?-thiazole urea inhibitors of MAP kinase p38α.Eur. J. Med. Chem.2012481-15.

Roseann Kroeker Sachs, et al. 3-Carbomethoxycyclopropen-3-yl Anion. Formation and Characterization of an Antiaromatic Ion. J. Am. Chem. Soc.,1994,116(2), 783-784.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H331-H302-H319

Highly flammable liquid and vapour. Toxic if inhaled. Harmful if swallowed. Causes serious eye irritation.

Precautionary Statements: P210-P261-P280-P240-P303+P361+P353-P305+P351+P338-P304+P340-P311-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
2039388
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2916.20
TSCA
Yes

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