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B20853 Methyl cyclopropanecarboxylate, 98%

CAS Number
2868-37-3
Synonyms
Cyclopropanecarboxylic acid methyl ester

Stock No. Size Price ($) Quantity Availability
B20853-14 25g 22.40
B20853-22 100g 65.10
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Methyl cyclopropanecarboxylate, 98%

MDL
MFCD00001280
EINECS
220-690-9

Chemical Properties

Formula
C5H8O2
Formula Weight
100.12
Boiling Point
118-119°
Flash Point
22°(71°F)
Density
0.983
Refractive Index
1.4180
Storage & Sensitivity
Ambient temperatures.
Solubility
Not miscible or difficult to mix in water.

Applications

It is primarily used an intermediate in the manufacture of pharmaceutical and agrochemical products. Methyl cyclopropane carboxylate is used as a reagent in the synthesis of N’-thiazole and N-pyrazole based inhibitors of MAP kinase p38α.

Notes

Store away from oxidizing agents and ignition sources. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from electrostatic charges.

Literature References

Matthäus Getlik, et al. Structure-based design, synthesis and biological evaluation of N-pyrazole, N?-thiazole urea inhibitors of MAP kinase p38α.Eur. J. Med. Chem.2012481-15.

Roseann Kroeker Sachs, et al. 3-Carbomethoxycyclopropen-3-yl Anion. Formation and Characterization of an Antiaromatic Ion. J. Am. Chem. Soc.,1994,116(2), 783-784.

GHS Hazard and Precautionary Statements

Hazard Statements: H225-H302-H311-H319

Highly flammable liquid and vapour. Harmful if swallowed. Toxic in contact with skin. Causes serious eye irritation.

Precautionary Statements: P210-P233-P240-P243-P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P312-P330-P337+P313-P362-P372-P374-P380-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Take precautionary measures against static discharge. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If eye irritation persists: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Explosion risk in case of fire. Fight fire with normal precautions from a reasonable distance. Evacuate area. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2039388
Hazard Class
3
Packing Group
II
Harmonized Tariff Code
2916.20
TSCA
Yes

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