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121-88-0 - 2-Amino-5-nitrophenol, 96% - 2-Hydroxy-4-nitroaniline - B20870 - Alfa Aesar

B20870 2-Amino-5-nitrophenol, 96%

CAS Number
121-88-0
Synonyms
2-Hydroxy-4-nitroaniline

Size Price ($) Quantity Availability
25g 24.82
100g 80.34
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2-Amino-5-nitrophenol, 96%

MDL
MFCD00007692
EINECS
204-503-8

Chemical Properties

Formula
C6H6N2O3
Formula Weight
154.13
Melting point
ca 200° dec.
Solubility
Insoluble in water. Solubility in methanol gives very faint turbidity. Soluble in alcohol, benzene, acetone, and diethyl ether.

Applications

2-Amino-5-nitrophenol has been used as starting material in the synthesis of series of (Z)-2-(substituted aryl)-N-(3-oxo-4-(substituted carbamothioyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl) hydrazine carboxamides, as semi permanent (nonoxidative) hair colorant and as toner in permanent (oxidative) hair dye products, in synthesis of series of 7-benzylamino-2H-1,4-benzoxazin-3(4H)-ones, anticonvulsant agents. Also used as a reactant for, diazotation and coupling reactions, preparation of biologically and pharmacologically active molecules. It is also applied in hair dyes and to make azo dyes.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Christina L Burnett, et al. Final report on the safety assessment of amino nitrophenols as used in hair dyes.Int J Toxicol.,2009,28(6), 217S-251S .

Nadeem Siddiqui, et al. Anticonvulsant and toxicity evaluation of newer 4H-benzo[1,4]oxazin-3-ones: The effect of two hydrogen bonding domains.Arch Pharm (Weinheim).,2010,343(11-12), 657-663.

GHS Hazard and Precautionary Statements

Hazard Statements: H341-H315-H319-H335

Suspected of causing genetic defects. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280h-P305+P351+P338

Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Beilstein
972974
Harmonized Tariff Code
2922.29
TSCA
Yes
RTECS
SJ6302500

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