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165047-24-5 - 2,4,5-Trifluorobenzaldehyde, 97% - B20986 - Alfa Aesar

B20986 2,4,5-Trifluorobenzaldehyde, 97%

CAS Number
165047-24-5
Synonyms

Size Price ($) Quantity Availability
1g 29.55
5g 98.80
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2,4,5-Trifluorobenzaldehyde, 97%

MDL
MFCD00061196
EINECS
000-000-0

Chemical Properties

Formula
C7H3F3O
Formula Weight
160.10
Boiling Point
174°
Flash Point
58°(136°F)
Density
1.408
Refractive Index
1.4820
Sensitivity
Air Sensitive
Solubility
Not miscible or difficult to mix in water.

Applications

It is a reactant in the enantioselective synthesis of (R)-selegiline, an anti-Parkinson's drug, (S)-benzphetamine, an anti-obesity agent, and (S)-sitagliptin, an anti-diabetic drug.

Notes

Store away from air and oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Stephen G. Davies, et al. Asymmetric synthesis of (-)-(R)-sitagliptin.Tetrahedron Lett.,201253(24), 3052-3055.

Linrong Zhu, et al. Design and Synthesis of 4-(2,4,5-Trifluorophenyl)butane-1,3-diamines as Dipeptidyl Peptidase IV Inhibitors.ChemMedChem.,2013,8(7), 1104-1116.

GHS Hazard and Precautionary Statements

Hazard Statements: H226-H315-H319-H335

Flammable liquid and vapour. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P280g-P305+P351+P338

Wear protective gloves. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Other References

Beilstein
8479631
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2913.00
TSCA
No

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