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3084-40-0 - Diethyl hydroxymethylphosphonate, tech. 85% - Hydroxymethylphosphonic acid diethyl ester - B21215 - Alfa Aesar

B21215 Diethyl hydroxymethylphosphonate, tech. 85%

CAS Number
3084-40-0
Synonyms
Hydroxymethylphosphonic acid diethyl ester

Size Price ($) Quantity Availability
5g 35.43
25g 95.69
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Diethyl hydroxymethylphosphonate, tech. 85%

MDL
MFCD00014418
EINECS
221-391-6

Chemical Properties

Formula
C5H13O4P
Formula Weight
168.13
Boiling Point
124-126°/3mm
Flash Point
110°(230°F)
Density
1.14
Refractive Index
1.444

Applications

Diethyl hydroxymethylphosphonate acts as a reactant for synthesis of α And β-dialkoxyphosphoryl isothiocyanate used in antiproliferative studies, dendritic polyglycerol anions for L-selectin inhibition, phosphonates for anti-HIV-1 activity, homo and copolymers of phosphonated norbornenes, Mitsunobu reactions. It is involved in studies of FBPase inhibition by phosphonic acid-containing thaizoles.

Notes

Incompatible with oxidizing agents. Store in a cool, dry condition in a well sealed container.

Literature References

Mateusz Psurski; Katarzyna Błażewska; Anna Gajda; Tadeusz Gajda; Joanna Wietrzyk; Józef Oleksyszyn. Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates. Bioorganic & Medicinal Chemistry Letters.2011, 21 (15), 4572-4576.

Marie Weinhart; Dominic Gröger; Sven Enders; Jens Dernedde; Rainer Haag. Synthesis of dendritic polyglycerol anions and their efficiency toward L-selectin inhibition. Biomacromolecules.2011, 12 (7), 2502-2511.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2931.90
TSCA
Yes

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