Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

B21250 Guanidine thiocyanate, 99%

CAS Number
593-84-0
Synonyms
Guanidine rhodanide

Stock No. Size Price ($) Quantity Availability
B21250-22 100g 64.60
B21250-36 500g 241.00
B21250-0E 2500g 991.00
Add to Cart Bulk/Specialty Print Quote View Item

Guanidine thiocyanate, 99%

MDL
MFCD00013027
EINECS
209-812-1

Chemical Properties

Formula
CH5N3•HSCN
Formula Weight
118.16
Melting point
118-122°
Density
1.29
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in water and ethanol

Applications

Guanidine thiocyanate is a useful tool for RNA isolation and protein solubilization. It is involved in the quantification of mRNA from hepatocytes. It acts as a medium for blood smaple lystae in order to maintain the integrity of nucleic acid. It is a chaotropic agent, mainly involved in the extraction of DNA and RNA. It is utilized to deactivate the influenza virus.

Notes

Light sensitive. Incompatible with acids and strong oxidizing agents.

Literature References

Chomczynski, P.; Sacchi, N. The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on. Nat. Protoc. 2006, 1 (2), 581-585.

van Doorn, H. R.; Bruijnesteijn van Coppenraet, E. S.; Duim, B.; Vandenbroucke-Grauls, C. M.; Weel, J. F.; Dankert, J.; Kuijper, E. J.; de Jong, M. D. Silica-guanidinium thiocyanate-based nucleic acid isolation protocol does not improve sensitivity of two commercial tests for detection of Mycobacterium tuberculosis in respiratory samples. Eur. J. Clin. Microbiol. Infect. Dis. 2006, 25 (10), 673-675.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H312-H314-H332-H335

Harmful if swallowed. Harmful in contact with skin. Causes severe skin burns and eye damage. Harmful if inhaled. May cause respiratory irritation.

Precautionary Statements: P260-P264b-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3563461
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
XL1225000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware