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4-Fluorophthalic anhydride is used in the preparation of 5-fluoro-2-pyridin-3-ylmethyl-isoindole-1,3-dione by reacting with C-pyridin-3-yl-methylamine.
Li, R. R.; Du, C. B.; Han, S.; Wang, J.; Yao, G. B.; Zhao, H. K. Saturated vapor pressure of 4-fluorophthalic anhydride and 4-chlorophthalic anhydride and isobaric vapor-liquid phase equilibrium of 4-fluorophthalic anhydride + 4-chlorophthalic anhydride: Measurement and modeling. Fluid Phase Equilib. 2015, 396, 35-42.
Kindahl, T.; Chorell, E. Efficient one-step synthesis of 4-amino substituted phthalimides and evaluation of their potential as fluorescent probes. Org. Biomol. Chem. 2014, 12 (25), 4461-4470.
Hazard Statements: H302-H315-H319-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.