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It finds its application oin the structure-activity studies of a series of dipyrazolo [3, 4-b: 3?, 4?-d] pyridin-3-ones binding to the immune regulatory protein B7. 1. It is also an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dye stuffs.
B. A. Shainyan, et.al. Reactions of N-sulfinyltrifluoromethanesulfonamide with carboxylic acids.Russ. J. Org. Chem.200844(8), 1121-1125.
Rémy C. Lemoine, et al. Exploration of a new series of CCR5 antagonists: Multi-dimensional optimization of a sub-series containing N-substituted pyrazoles.Bioorg. Med. Chem. Lett., 201020(16), 4753-4756.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.