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3-(2-Furyl)acrylic acid is a reactant used in the preparation of heteroaryl-substituted bis-trifluoromethyl carbinols and trifluoroacetophenone derivatives malonyl-CoA decarboxylase (MCD) inhibitors.
Wallace, D. et al. Novel trifluoroacetophenone derivatives as malonyl-CoA decarboxylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 2007, 17 (4), 1127-1130.
Frederick E. Brot; Myron L. Bender. Use of the specificity constant of .alpha.-chymotrypsin. J. Am. Chem. Soc., 1969 , 91(25), 7187-7191.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.