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1-Methyl-1-cyclohexanecarboxylic acid was used as internal standard during the determination of valproic acid metabolites. Also been used as an anticonvulsant drug and causes maturation of murine neuroblastoma cells in vitro. Used in the synthesis of p38 map kinase.
A J Sadeque et. al. Human CYP2C9 and CYP2A6 mediate formation of the hepatotoxin 4-ene-valproic acid. Journal of Pharmacology and Experimental Therapeutics, 1997, 283 (2), 698-703.
S A Fischkoff; and E Walter. Induction of neutrophilic differentiation of human promyelocytic leukemic cells by branched-chain carboxylic acid anticonvulsant drugs. Journal of biological response modifiers, 1984, 3(3), 132-137.