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1197-18-8 - trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97% - B21742 - Alfa Aesar

B21742 trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97%

CAS Number
1197-18-8
Synonyms

Size Price ($) Quantity Availability
10g 52.70
50g 164.00
250g 498.00
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trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97%

MDL
MFCD00001466
EINECS
214-818-2

Chemical Properties

Formula
C8H15NO2
Formula Weight
157.21
Melting point
>300°
Solubility
Soluble in water (167 mg/ml), ethanol (<1 mg/ml at 25°C). Very slightly soluble in ether, DMSO (<1 mg/ml at 25°C), and alcohol.

Applications

It is an antifibrinolytic agent that is found to inhibit plasmin-induced fibrinolysis. Used in various hemorrhagic diseases , abnormal bleeding in operations. It is also used as a lysine analogue to characterize binding sites in plasminogen.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

J M Marshall, et al. Conformational studies of human plasminogen and plasminogen fragments: evidence for a novel third conformation of plasminogen.Biochem.,199433/span>(12), 3599-3606.

G J Hoover et. al. Amino acids of the recombinant kringle 1 domain of human plasminogen that stabilize its interaction with µ-amino acids.Biochemistry.,199332(41), 10936-10943.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,9569
Beilstein
2207452
Harmonized Tariff Code
2922.49
TSCA
No
RTECS
GU8400000

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